Anti-human renal cell carcinoma (clone RC38)
"Binding of RC38 monoclonal antibodies to human renal cell carcinoma"
Hybridoma Clone Antibody Isotype Cat. No.
RC38 Mouse IgG1 ARA38
Source
A mouse was immunized with a renal cell carcinoma homogenate. After fusing the spleen cells
from this mouse with myeloma cells, antibody-producing cells were screened on thin sections
of various human tissues and selected based on staining pattern.
Specification:
RC38 stains over 95% of primary renal cell carcinomas and 60% of metastases of renal cell
carcinoma and glomerular visceral epithelium and proximal tubules in normal kidney (cytoplasmic).
It does not stain epithelial cells of non-renal malignancies.
| | Immunohistochemistry (frozen sections) | yes |
| | Immunohistochemistry (formalin embedded tissue) | no |
| | Immunohistochemistry (antigen retrieval) | no |
| | Flow cytometry | not tested |
| | Immunoblotting | not tested |
| | ELISA | not tested |
| | RIA | not tested |
| | Cross reactivity: |
| | Other tumors | not detected |
| | Endothelial cells in tumors | frequently positive |
| | Mouse renal tumors | not tested |
| | Rat renal tumors | not tested |
| | Rabbit renal tumors | not tested |
| | Goat renal tumors | not tested |
Immunoglobulin (sub)class: IgG1
Presentation: supernatant
Storage:
4°C = 2 months
-20°C = 1 year
Aliquoted storage at -70°C or –20°C is recommended.
Reference:
1. Oosterwijk E et al. (1986). Am J Pathol 123, 301-309.
2. Dijk J. van (1988) J Nucl Med 29, 1087-1082.
Ordering Information
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